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Conceptual Development of Industrial Biotechnology for Commercial Production of Vaccines and Biopharmaceuticals
Basanta Kumara Behera
Paperback. Academic Press 2023-03-01.
ISBN 9780443187483
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Publisher description
Conceptual development of biotechnology has taken a new shape and style with the integration of medical sciences, physical science, and engineering, in developing microbial or cell line process technology and their application for large-scale isolation and purification of metabolites or vaccines through the fermentation process.These metabolites are in the form of biologic drugs which are widely used in biopharmaceutical, biochemical, food, nutraceuticals, and diagnostics. The current global market for vaccines, especially COVID-19, is tremendous. Bivalent oral polio vaccine, diphtheria, tetanus-containing, and measles-containing vaccines have a high demand internationally and recombinant DNA technology and protein engineering are helpful in the production of quality bio-products. Conceptual Development of Industrial Biotechnology for Commercial Production of Biopharmaceuticals and Vaccines provides insight on how to bring sustainability into biologic drugs production. The cumulative facts and figures within in the book are helpful to promoters in monitoring value chain transfer process of super quality biologics for better return, in terms of profits. In addition, it is a useful reference for the students, researchers, and scientists belonging to biotechnology, pharmaceutical science, medical sciences, and the R&D division of biotechnology-based industries, to understand the latest information on industrial biotechnology and how to apply that learning to be an entrepreneur and develop start-up projects for the commercialization of biologics. Informs how biotechnology and pharmaceutical industries act as central pillars for stable production of value-added biological drugs and vaccines from genetically engineered suitable vectors like microbe or cell lines from animals, mammals, or plants Highlights various traditional and modern techniques used for improvising the quality of suitable vectors to produce biologic drugs and vaccines under GMP manufacturing facilities Provides updated information on latest microchip-based bioreactors, disposable bag bioreactors and animal systems as bioreactors to produce biologic drugs like Smart Biomolecules (next generation therapeutics), Bio-similar drugs, Bio-betters, and antibody-drug conjugates Explains how the closed bioreactors with proper mechanical amendments are used for vaccine production
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Conceptual Development of Industrial Biotechnology for Commercial Production of Vaccines and Biopharmaceuticals
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